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Adolescent Wellness And Reproductive Education Foundation

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A Common Sense Secret to a Safer Pregnancy and a Healthier Baby

A pregnancy with peace of mind. A baby born free of birth defects, diseases, or other disorders. They are every woman's dream.

While no one can promise you perfection, a wide range of medical advances can give you a precious degree of control over your child's future and your own health during pregnancy. The secret is preconceptional care. A valuable form of preventive medicine, preconceptional care simply means seeing your doctor or midwife for an exam—before you conceive

During your preconceptional visit, your practitioner can point out any special hazards you and your future baby may face. He or she can offer you testing, immunizations, counseling, nutritional therapy, or other treatment to help ward off problems before they happen.

Among the women most likely to benefit from preconceptional care are those with diabetes, phenylketonuria (PKU), and certain infectious or hereditary diseases. However, because spontaneous miscarriages occur in about 25% of all pregnancies, it makes sense to schedule a pre-pregnancy exam even if you do not fall into any high-risk categories. Don't be surprised if your health care provider offers you preconceptional care on a routine gynecologic visit. Unintended pregnancies do happen. Staying healthy and informed "just in case" while you are in your reproductive years can be a big benefit. In addition, your healthcare provider can offer you valuable general or pre-pregnancy contraceptive advice during your preconceptional visit.

Why Preconceptional Care Can Be Vital

Before you realize you've even missed a menstrual period—as early as 17 days after sperm and ovum meet—the cells of the rapidly growing life within you are starting to differentiate into tissue that will form your baby's heart and other organs. Most fetal development, in fact, occurs within the three months after conception. The baby's heart begins to beat after 4 weeks. By 8 weeks your child's eyes, ears, nose, mouth, fingers, and toes are recognizable. And by 12 weeks most major organs have developed.

It is during this very early time of organ formation that your fetus is most vulnerable to teratogenic (birth-defect-inducing) drugs, viruses, chemicals, and other agents. By working with your doctor, nurse practitioner or midwife, you can guard against these toxins before you conceive and remove many serious threats to your baby.

Additionally, your family medical history may make you—or your partner—a carrier of certain serious genetic diseases. If so, you are well advised to obtain preconceptional counseling to reduce the risk of passing these disorders on to your child. Again, planning ahead before your start your pregnancy is the key. Once conception occurs, the genetic material is in place and it is too late for preventive measures.

Your Reproductive History Offers Important Clues and Insights

Even if you have had previous miscarriages, premature births, difficulties conceiving, or other obstetrical or gynecological problems, your physician may be able to help you avoid problems in a future pregnancy. During a preconceptional exam, he or she will perform a pelvic exam. Based on your medical history and physical findings, your practitioner will order any special tests that may be necessary. By obtaining an accurate diagnosis and medical treatment before you attempt to conceive, you can significantly improve your chances of having a healthy baby.

Genetic Detective Work and Counseling Can Help You Protect Your Child

Genetic testing and, if necessary, counseling are among the most critical preconceptional services you can obtain. If your practitioner suspects you could be a carrier of a hereditary disorder, he or she can help you obtain genetic screening through blood tests. Once a pregnancy has begun, genetic testing of the fetus can be done through amniocentesis and chorionic villus sampling (CVS).

Depending on the outcome of the tests, your doctor can counsel you on a range of available options. In light of the severity of many of these diseases, it is easy to see why prevention is so important. In some cases, screening for certain diseases is based on your race or ethnicity. Persons of African, Mediterranean, Middle Eastern, Caribbean, and Latin American heritage are in a risk group for sickle-cell anemia, an abnormality of the red blood cells. Beta-thalassemia, a type of anemia that is related to sickle-cell anemia, tends to occur in persons of Mediterranean origin (especially Italians), Southeast Asians, Indians, Pakistanis, and Africans. Another form of thalassemia affects Southeast Asians and Africans. Persons affected by these painful diseases run an increased risk of dying as young adults.

Yet another ethnically related genetic disorder, Tay-Sachs disease, affects persons of Eastern European Jewish and French-Canadian origin. Tay-Sachs affects the central nervous system and leads to death in early childhood.

Other genetic diseases, though not ethnically related, may run in families. These include cystic fibrosis, fragile X, and Down syndromes. Older mothers are at additional risk for having a baby with Down syndrome, a condition that involves moderate to severe mental retardation in addition to facial and other abnormalities. Phenylketonuria (PKU) is another genetic disorder that can result in mental retardation. Effective interventions are available to minimize the risks of PKU.

With Pre-Pregnancy Precautions and Immunizations, You Can Avoid a Number of Problems and Gain Peace of Mind

Do you have insulin-dependent (Type I) diabetes? If so, you will want to see your doctor to achieve the best possible control of your blood sugar before you conceive… as well as throughout your pregnancy. That's because maintaining excellent blood glucose control significantly reduces your risk of having a baby with congenital malformations. Also by maintaining tight control of your glucose, you will protect yourself from complications during pregnancy. A number of other diseases can make pregnancy risky for you. Your practitioner can help you understand and meet these challenges. Your preconceptional exam is a critical first step.

During pregnancy, both rubella (German measles) and hepatitis B virus can harm your developing fetus. You can, however, obtain immunizations against both of these infectious diseases as part of your preconceptional care. If contracted early in pregnancy, rubella may affect your baby's eyes, ears, and heart. Hepatitis B virus, which is often sexually transmitted, can also be passed from mother to baby. Women with hepatitis B virus can give birth to infants who are likely to become carriers of the disease and to suffer serious liver-related effects. If you are a health worker or if you may have had sexual contact with another hepatitis B carrier, you may be at risk for hepatitis B virus. Your doctor or midwife can help you avoid these dangers through pre-pregnancy treatment.

You can obtain preconceptional testing for a number of other infectious diseases that could put your fetus at risk. These include toxoplasmosis (found among cat owners and people who handle raw meat), tuberculosis and cytomegalovirus (health workers in neonatal intensive care units, child care centers, or dialysis units are in this risk group). In addition, your doctor or midwife should offer you confidential AIDS testing and appropriate counseling…as well as testing and treatment for any sexually transmitted diseases to which you may have been exposed. These may include gonorrhea, chlamydia, and syphilis.

Diet and Medication Changes for a Healthier Start

The prescription and non-prescription medications you take can effect your pregnancy, even from its earliest moments. For example, if you are taking Accutane® for severe acne, your obstetrician or midwife will counsel you to halt the drug as it is linked to a high incidence of birth defects. Depending on what medication you are taking for any pre-existing illness or condition, your doctor may be able to switch you to a drug that provides the therapy you need—without possible birth-defect-inducing side effects.

In some cases your doctor or midwife will recommend you gain or lose weight before starting a pregnancy. If you are a vegetarian, he or she may suggest modifications to your diet to ensure that your developing child receives adequate nutrients. Be sure to discuss any food cravings you may have and which vitamin supplements you take. Megadoses of vitamins A, B6, C, D, E, K, or too much iron, zinc, or selenium can be harmful during pregnancy. Again, see your physician or other provider for guidance.

Finally, if you have phenylketonuria (PKU), a disorder that prevents the liver from metabolizing a certain amino acid called phenylalanine, you will need to observe special dietary restrictions. Your doctor will strongly advise you to stop using the artificial sweetener Aspartame—sometimes sold as NutraSweet, Equal or under other brand names—and foods or beverages that contain Aspartame. Women with PKU who have high blood levels of phenylalanine during pregnancy are likely to give birth to children with mental retardation and other congenital abnormalities. By lowering phenylalanine levels during early pregnancy you can reduce these risks.

Folic Acid Supplements: The Newest Way to Protect Your Future Baby's Nervous System

One of the most promising new pre-conceptional recommendations is a daily dose of folic acid. Folic acid is one of the vitamins in the B-complex. It has been shown to dramatically reduce the risk of abnormalities of the spinal column, such as spina bifida, particularly when taken from the earliest days of pregnancy. Your health care provider will prescribe the dosage and course that's best for you. While all women who may become pregnant can benefit from folic acid supplementation, the therapy is especially recommended to women with a history of fetal neural tube defects.

Avoiding Alcohol, Tobacco, and Other Addictive Drugs

Some of the most common neonatal problems are also the most preventable. While smoking and taking addictive drugs are always bad for your health, you should take special measures to kick these habits as you plan a pregnancy. These substances can cause your baby to be born both prematurely and at a low birth weight. Alcohol, too, can interfere with fetal growth. In addition, it can cause a tragic set of symptoms known as fetal alcohol syndrome. This can involve mental retardation, facial deformities and other defects. Even though drinking is very much a part of our culture, there is no known "safe" level of alcohol intake during pregnancy. That is why you should abstain from beer, wine, or hard liquor in anticipation of a pregnancy. Should you need help breaking any alcohol, tobacco, or other drug habits, do not hesitate to ask your health care provider for guidance.

Pre-Pregnancy Contraception Strategies

Depending on what form of birth-control you are now using, your doctor or midwife may recommend a pre-pregnancy change. For example, your doctor may advise you to stop the Pill and switch to another form of contraception for a few months before you attempt a pregnancy. Women should not take oral contraceptives if they know or suspect that they might be pregnant.

Looking Ahead with Confidence

Think of preconceptional care as a vital introduction to your later prenatal care. In many cases, a woman's preconceptional exam will reveal no problems at all. Your doctor may suggest something as simple as a temporary change in your pre-pregnancy birth control methods and daily folic acid. Also keep in mind that, on average, it takes couples having unprotected intercourse from nine months to one year to achieve a pregnancy. If you do not get pregnant after trying for one year, do consult your doctor for guidance.

Most babies are born healthy. Still, it makes sense to take basic preconceptional precautions, especially if you fall into a risk group. Remember, accepting your health care provider's interventions is up to you. You may choose to work with your provider to lessen your specific hazards… accept the risks…or explore other alternatives. If you are in your reproductive years now, consider a preconceptional visit to give your future child a healthy and loving start.

Your Preconceptional Exam Checklist

The ideas in this article are based on information provided in ACOG Technical Bulletin Number 205, "Preconceptional Care."